Polygenic inheritance and micro/minisatellites
نویسندگان
چکیده
منابع مشابه
Genetic drift and polygenic inheritance.
The interaction of random gene drift and selection was studied by computer simulation for two quantitative traits, which were considered to approximate stature and skin color dlfferences in human populations. The expected effects of gene drift, fixation of alleles and reduction of genotypic and phenotypic variances, were found in the simulation. Stabilizing selection, which seems to be the type...
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Inheritance is the process where genetic information is transferred from the parent to offspring. The information that is transferred is stored in genes, which are Deoxyribose Nucleic Acid (DNA)fragments that codes for specific proteins that are functional and could be transferred. Each gene consists of a pair of alleles that determine the character and as Mendelian Genetics suggests, these all...
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Non-stationary function optimization has proved to be a di cult subject for genetic algorithms (GAs). Standard haploid GAs nd it di cult to track a moving target and tend to converge to a local optimum that appears early in a run. We have surveyed a number of diploid GAs which use classic dominant recessive expressions, and outline some possible reasons why they have failed to gain wide accepta...
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STUDY HYPOTHESIS Susceptibility to inherited cryptorchidism in the LE/orl rat may be associated with genetic loci that influence developmental patterning of the gubernaculum by the fetal testis. STUDY FINDING Cryptorchidism in the LE/orl rat is associated with a unique combination of homozygous minor alleles at multiple loci, and the encoded proteins are co-localized with androgen receptor (A...
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A general linear model of combined polygenic-cultural inheritance is described. The model allows for phenotypic assortative mating, common environment, maternal and paternal effects, and genic-cultural correlation. General formulae for phenotypic correlation between family members in extended pedigrees are given for both primary and secondary assortative mating. A FORTRAN program BETA, availabl...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 1998
ISSN: 1359-4184,1476-5578
DOI: 10.1038/sj.mp.4000289